منابع مشابه
Iron regulation by hepatocytes and free radicals
Iron is an essential metallic microelement for life. However, iron overload is toxic. The liver serves an important role as a storehouse for iron in the body. About 20-25 mg of iron is required each day for hemoglobin synthesis. To maintain iron homeostasis, transferrin and transferrin receptors are primarily involved in the uptake of iron into hepatocytes, ferritin in its storage, and ferropor...
متن کاملIron, free radicals, and oxidative injury.
Iron metabolism and superoxide metabolism are clearly interactive, especially under pathological conditions. Each can exacerbate the toxicity of the other. Iron overload may amplify the damaging effects of superoxide overproduction in a very broad spectrum of inflammatory or ischemia-related conditions. Furthermore, chronic oxidative stress may modulate iron uptake and storage, leading to a sel...
متن کاملFree Radicals and Gastric Cancer
Mahmoud Lotfy1 and Yousery E. Sherif2 1Associate Professor of Molecular Cell Biology & Immunology, Molecular and Cellular Biology Department, Genetic Engineering and Biotechnology Research Institute, Minufiya University, Sadat City, Minufiya, Egypt and Department of Applied Medical Sciences, Jouf University, Qurayat, 2Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, M...
متن کاملFree radicals and breast cancer.
The 3D-partner is a web tool to predict interacting partners and binding models of a query protein sequence through structure complexes and a new scoring function. 3D-partner first utilizes IMPALA to identify homologous structures (templates) of a query from a heterodimer profile library. The interacting-partner sequence profiles of these templates are then used to search interacting candidates...
متن کاملFree radicals and breast cancer.
For the most part, the article in the Forum section titled "Free Radicals and Breast Cancer" [EHP 104:82 1 (1996)] accurately describes our paper "Progression of Human Breast Cancers to the Metastatic State Is Linked to Hydroxyl Radical-induced DNA Damage" (1). However, it was claimed that Some scientists have questioned the methodologies used by Malins and note that studies published in the Fe...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1990
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19900027